Androgen Deprivation Therapy for Prostate Cancer Treatment

Androgens are hormones that nurture male characteristics such as sexual function, muscle mass, and facial hair. The main androgen is the testosterone. Prostate cancer cells require androgens to develop. Androgen deprivation therapy (ADT) is a kind of treatment for prostate cancer blocking the effects or production of testosterone and other male hormones.

ADT is used to treat:

  • Cancer that has grown outside the prostate
  • Return of prostate cancer after another therapy has been used
  • Men who are experiencing high risk of cancer return after surgery or radiation therapy

Another name for ADT is “Hormone therapy.” Though these terms can be used identically, prostate cancer uses ADT. This treatment influences the whole body rather than a particular area.


What Are Androgens? 

Male sex hormones are called as androgens. The two most common androgens are dihydrotestosterone (DHT) and testosterone. Women have few androgens too. Like all hormones, androgens influence the actions of tissues and cells in the body. Most testosterone is generated in the testicles, but a slight amount is made by the adrenal glands (just above the kidneys). Testosterone is also produced by prostate cancer cells.

What Do Prostate Cancer And Androgens Have To Do With Each Other?

Androgens are required to ensure that the prostate develops and functions normally. They can lead to prostate cancer because it binds to and activates the “androgen receptor,” a protein that is made by the cells in the prostate gland. When the androgen receptors have been jumped to androgen, they then generate individual genes that cause prostate cells to develop.

At an early period of prostate cancer, they “feed off” androgens, depending on them to increase. These kinds of prostate cancers are known as “androgen-sensitive” and “androgen-dependent.” ADT works to ‘deny’ these prostate cells of androgen, thus slowing down.

What Can A Patient Expect From ADT? 

ADT is used in numerous ways to cure prostate cancer.

  • Combination ADT: Anti-androgens are combined with either a surgical removal of the testicles or LHRH agonist.
  • Intermittent ADT: ADT is once concluded the PSA number is reduced and stabilized. ADT has started again when the PSA number rises again.

Prostate Cancer Surgery Cost

Prostate cancer treatment in India is performed at best hospitals along with the best panel of highly trained doctors and their medical team. Prostate cancer surgery cost in India is very much affordable when compared to western countries. With the improvement in technology like a robotic arm for prostate operation, the rate of success for prostate cancer treatment has gone above by many folds. Robotic operations for prostate cancer permits maximum precision during the surgery making it the safest bet for the patients even at old age.


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